Palladium-catalyzed synthesis of beta-lactams via carbonylative cycloaddition of benzyl and allyl halides with imines

Citation
Cs. Cho et al., Palladium-catalyzed synthesis of beta-lactams via carbonylative cycloaddition of benzyl and allyl halides with imines, SYN COMMUN, 29(15), 1999, pp. 2695-2703
Citations number
27
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNTHETIC COMMUNICATIONS
ISSN journal
00397911 → ACNP
Volume
29
Issue
15
Year of publication
1999
Pages
2695 - 2703
Database
ISI
SICI code
0039-7911(1999)29:15<2695:PSOBVC>2.0.ZU;2-Y
Abstract
Benzyl and allyl halides react stereoselectively with imines under carbon m onoxide pressure in the presence of a catalytic amount of bis(triphenylphos phine)palladium(II) chloride together with triethylamine to afford the corr esponding beta-lactams in good yields.