Hypervalent iodine oxidation of indolic 2-oxazolines

Authors
Braun, NA Bray, JD Ciufolini, MA
Citation
Na. Braun et al., Hypervalent iodine oxidation of indolic 2-oxazolines, TETRAHEDR L, 40(27), 1999, pp. 4985-4988
Citations number
16
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
40
Issue
27
Year of publication
1999
Pages
4985 - 4988
Database
ISI
SICI code
0040-4039(19990702)40:27<4985:HIOOI2>2.0.ZU;2-W
Abstract
A novel oxidation of indolic 2-oxazolines with iodobenzene diacetate leads to unusual spiroheterocycles of potential interest in synthetic and medicin al chemistry. In several instances, addition of 2,2,2-trifluoroethanol (the solvent for such oxidations) to the substrates was observed. (C) 1999 Else vier Science Ltd, All rights reserved.