M. Wieser et al., Synthesis of (S)-1-(4-hydroxyphenyl)alcohols by eugenol dehydrogenase fromPseudomonas fluorescens E118, TETRAHEDR-A, 10(9), 1999, pp. 1627-1630
(S)-1-(4-Hydroxyphenyl)ethanol and (S)-1-(4-hydroxyphenyl)propanol were syn
thesized with enantiomeric excesses of 96.6% and 95.2%, respectively, from
the corresponding 4-alkylphenols by eugenol dehydrogenase from Pseudomonas
fluorescens E118. The enantioselectivity of the enzyme was shown to be pH-d
ependent. (C) 1999 Elsevier Science Ltd. All rights reserved.