Synthesis of C-2-symmetrical 1,1 '-disubstituted ferrocenyl amino alcoholsand use in catalytic asymmetric addition of diethylzinc to benzaldehyde

Authors
Bastin, S Delebecque, N Agbossou, F Brocard, J Pelinski, L
Citation
S. Bastin et al., Synthesis of C-2-symmetrical 1,1 '-disubstituted ferrocenyl amino alcoholsand use in catalytic asymmetric addition of diethylzinc to benzaldehyde, TETRAHEDR-A, 10(9), 1999, pp. 1647-1651
Citations number
24
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON-ASYMMETRY
ISSN journal
09574166 → ACNP
Volume
10
Issue
9
Year of publication
1999
Pages
1647 - 1651
Database
ISI
SICI code
0957-4166(19990507)10:9<1647:SOC1'F>2.0.ZU;2-L
Abstract
Optically active C-2-symmetrical 1,1'-disubstituted ferrocenyl amino alcoho ls have been used as chiral catalysts in the asymmetric addition of diethyl zinc to benzaldehyde. 1-Phenylpropanol has been obtained in up to 83% enant iomeric excess. (C) 1999 Published by Elsevier Science Ltd. All rights rese rved.