N-tert-butoxycarbonyl-N,N '-ethylene-bridged (S)-tyrosyl-(S)-tyrosine methyl ester

Authors
Yamato, K Miyake, H Hirotsu, K Kojima, Y
Citation
K. Yamato et al., N-tert-butoxycarbonyl-N,N '-ethylene-bridged (S)-tyrosyl-(S)-tyrosine methyl ester, ACT CRYST C, 55, 1999, pp. 1023-1025
Citations number
17
Categorie Soggetti
Physical Chemistry/Chemical Physics
Journal title
ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS
ISSN journal
01082701 → ACNP
Volume
55
Year of publication
1999
Part
6
Pages
1023 - 1025
Database
ISI
SICI code
0108-2701(19990615)55:<1023:N'(M>2.0.ZU;2-Q
Abstract
The title compound, a pseudopeptide, methyl (2S)-3-(4-hydroxyphenyl)-2-[(3S )-4-(tert-butoxycarbonyl)-3-(4-hydroxybenzyl)-2-oxopiperazin-1-yl]propionat e, C26H32N2O7, was crystallized from an H2O/methanol solution. The two N-su bstituted chains on the piperazin-2-one (MKP) ring lie in the quasi-equator ial position and the third chain lies in the quasi-axial position. Each sid e chain on the tyrosines is located opposite the MKP ring. The MKP ring has a pseudo-chair form.