Most women who are diagnosed with breast cancer have either no risk factors
or only one. Recommendations for breast cancer screening for women between
the ages of 40 and 49 are controversial, because the National Institutes o
f Health (NIH) Consensus Conference made no specific recommendation regardi
ng the frequency of screening. In so doing, a possible reduction in mortali
ty or morbidity is balanced against known false-positive or false-negative
rates and the detection of ductal carcinoma in situ. Although genetic testi
ng is available, many questions surround its use, including its likely emot
ional and financial impact on the patient and her family and the unresolved
issue of how to interpret the results.