Long-term intraspinal infusions of opioids with a new implantable medication pump

Citation
R. Likar et al., Long-term intraspinal infusions of opioids with a new implantable medication pump, ARZNEI-FOR, 49(6), 1999, pp. 489-493
Citations number
10
Categorie Soggetti
Pharmacology & Toxicology
Journal title
ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH
ISSN journal
00044172 → ACNP
Volume
49
Issue
6
Year of publication
1999
Pages
489 - 493
Database
ISI
SICI code
0004-4172(199906)49:6<489:LIIOOW>2.0.ZU;2-U
Abstract
Experiences with long-term intraspinal infusion of opioid drugs using the n ew implantable medication pump VIP 30 in patients with chronic non-malignan t pain are reported. During a 19-month period 10 patients with chronic pain - mainly mixed nociceptive-neuropathic pain underwent implantation of the medication pump for long-term treatment. The mean followup period was 9.5 m onths. Pain relief was classified as very good in 22.2 %, good in 44.4 %, m oderate in 22.2 % and poor in 11.1 %. In 88.9 % of the cases the patients s tated they would undergo the same procedure again. Technical problems (cath eter dislocation) developed in 1/10 patients could be surgically corrected. One pump including catheter was explanted because of an infected seroma wi thin the pocket area. Long-term intrathecal application of opioids with the VIP 30 pumps is an effective and safe treatment in patients with chronic n on-malignant pain.