The purpose of this study was to establish the temporal stability of l
ipid responses to acute psychological stress. Eighteen men were tested
twice an average of 16.2 months apart in identical laboratory reactiv
ity protocols. Total cholesterol, triglycerides, high- and low-density
lipoprotein-cholesterol, plasma volume, heart rate, and blood pressur
e were assessed during rest, serial subtraction, and speech. After cor
rection for changes in plasma volume, significant elevations were reco
rded for all variables during the speech task, but fewer variables sho
wed changes during the serial subtraction task. Strong intersession as
sociations were found when considering levels of the variables during
baseline and stress (rs greater than or equal to .58). Correlations fo
r the change scores ranged from .36 to .52 for the atherogenic lipids
and from .39 to .87 for the cardiovascular variables. Little evidence
was found for stability of plasma volume changes. There is moderate to
high temporal stability of the atherogenic lipids when considering re
st and stress levels and small to moderate temporal stability when con
sidering change scores.