BONE DYSPLASIAS, NONTRADITIONAL MECHANISMS OF INHERITANCE AND MONOZYGOTIC TWINS

Authors
HALL JG LOPEZRAUGEL E
Citation
Jg. Hall et E. Lopezraugel, BONE DYSPLASIAS, NONTRADITIONAL MECHANISMS OF INHERITANCE AND MONOZYGOTIC TWINS, Pediatric radiology, 27(5), 1997, pp. 422-427
Citations number
39
Categorie Soggetti
Radiology,Nuclear Medicine & Medical Imaging",Pediatrics
Journal title
Pediatric radiology → ACNP
ISSN journal
03010449
Volume
27
Issue
5
Year of publication
1997
Pages
422 - 427
Database
ISI
SICI code
0301-0449(1997)27:5<422:BDNMOI>2.0.ZU;2-J
Abstract
New developments in the area of cytogenetics and molecular genetics ha ve suggested a variety of newly recognized mechanisms that result in h uman genetic disorders. These mechanisms are being observed among indi viduals with bone dysplasias. Mosaicism imprinting, parent-of-origin d ifferences, uniparental disomy (UPD) and monozygotic twinning represen t mechanisms which modify the phenotypic expression of the bone dyspla sia.