Variance components in the context of Generalizability Theory are useful in
dices for attributing the amount of variance to a particular facet or objec
t of measurement. The mean difference effect size (MDES) has proven to be a
useful tool both in synthesizing the results of multiple studies and in in
terpreting individual study results. A mathematical relationship is drawn,
therefore, between the variance components of a nested two-facet design con
figuration on the one hand, and the MDES that can be calculated from the de
scriptive statistics of an hypothetical measurement study on the other. Usi
ng two different variance components estimation procedures, we show that th
e relationship is both statistically and conceptually meaningful in that al
l of these estimates closely approximates the true Glassian MDES.