I. Chudoba et al., High resolution multicolor-banding: a new technique for refined FISH analysis of human chromosomes, CYTOG C GEN, 84(3-4), 1999, pp. 156-160
A new multicolor-banding technique has been developed which allows the diff
erentiation of chromosome region specific areas at the band level. This tec
hnique is based on the use of differently labeled overlapping microdissecti
on libraries. The changing fluorescence intensity ratios along the chromoso
mes are used to assign different pseudo-colors to specific chromosome regio
ns. The multicolor banding of human chromosome 5 is presented as an example
.