The aim of the present study was to determine the effect of pesticides on t
he plasma levels of amino acids and serum liver enzymes in farm workers in
the United Arab Emirates. This case-control study consisted of 103 farm wor
kers (case) and 105 non-farm workers (control), matched for age, sex, and n
ationality selected from Al-Ain City, Dubai, Sharjah, and Fujairah Emirates
. The Indian-subcontinent workers represented the majority among farmers (9
0.3%) and non-farmers (82.9%). Seventy percent of the subjects reported wor
king in a field with an obvious chemical smell and 60% of the farm workers
reported mixing pesticides and spraying with chemical pesticides. Amino aci
d analysis showed higher values among farmers than non-farmers for histidin
e, threonine, lysine, and arginine as essential amino acids (p<0.0001). Orn
ithine, taurine, glutamic, serine glycine, and tryptophan as non-essential
amino acids showed significantly higher values in farmers when compared wit
h the non-farmers (p<0.0001). (C) 1999 Elsevier Science Ltd.