G. Alvaro et al., Synthesis of N,N '-disubstituted (1R,2R)-1,2-diaminocyclohex-4-enes by a ruthenium-catalyzed ring-closing metathesis reaction, EUR J ORG C, (7), 1999, pp. 1523-1526
Enantiopure (1R,2R)-1,2-diaminocyclohex-4-ene derivatives have been synthes
ized by the ruthenium-catalyzed ring-closing metathesis reaction of (4R,5R)
-N,N'-bis [(S)-1-phenylethyl]-4,5-diamino-1,7-octadiene dihydrochloride.