C-1 ' radicals in nucleosides

Authors
Chatgilialoglu, C
Citation
C. Chatgilialoglu, C-1 ' radicals in nucleosides, FARMACO, 54(5), 1999, pp. 321-325
Citations number
20
Categorie Soggetti
Pharmacology & Toxicology
Journal title
FARMACO
ISSN journal
0014827X → ACNP
Volume
54
Issue
5
Year of publication
1999
Pages
321 - 325
Database
ISI
SICI code
0014-827X(19990530)54:5<321:C'RIN>2.0.ZU;2-T
Abstract
C-1' radicals in modified nucleosides have been generated by a variety of m ethods. Synthetic methodologies based on radical cascade reactions for the preparation of anomeric spironucleosides have been developed. Structural in formation on C-1' radicals has been obtained and their fate in anoxic or ae robic conditions has been studied. (C) 1999 Elsevier Science S.A. All right s reserved.