OBJECTIVE: To evaluate the usefulness of osmotic dilators as an altern
ative to diagnostic cone biopsy. STUDY DESIGN: Women who had an unsati
sfactory colposcopic examination were offered repeat examination after
use of osmotic dilators as part of an interventional, nonrandomized s
tudy. The physician selected the type, size and duration of use of the
dilator. RESULTS: Twenty-nine of 32 women (91%) underwent a satisfact
ory repeat examination. Diagnostic cone biopsy was avoided in all wome
n. Twenty-one women did not require further treatment, and four women
had the lesion removed by the colposcopically directed biopsy. Six wom
en underwent electrosurgery, and one woman underwent cryotherapy. CONC
LUSION: The use of osmotic dilators can decrease the need for diagnost
ic cone biopsy.