Background information: Human immunodeficiency virus/acquired immune defici
ency syndrome (HIV/AIDS) is a major public health problem in India. In gene
ral, it affects mainly young people who are at their most productive part o
f life. Despite initial fears that AIDS will be disastrous for the economy,
recent experience and estimations have shown that there is a need for reap
praisal of its economic impact on society. Research question: From the view
point of the society of India, what is the total cost and equivalent annual
cost of HIV infections for the period 1986-1995 (10 years) in India? Metho
ds: Type of analysis: Cost-descriptive based on predictive modelling cohort
analysis using human capital approach. A, discount rate of 5% was used. Th
e cost of HIV infections include (i) loss of productivity among HIV patient
s due to sickness and death, (ii) productivity loss due to caregivers of AI
DS patients, and (iii) cost of management of AIDS patients. To estimate the
loss of productivity due to premature death attributable to AIDS, a life t
able approach using two cohorts, one with and one without HIV/AIDS infectio
n at assumed rates was used. The demographic data of 1991 census were used.
The difference in the person-years lived in the two scenarios gave the per
son-years lost due to HIV/AIDS. This was calculated separately for rural an
d urban areas. To convert this to monetary terms, national per capita incom
e for 1992-93 of Rs. 5529 was used. The data on the days of inpatient care
and the cost of management of AIDS patients were based on currently availab
le data and 'expert opinion'. We analysed, using three different sets of as
sumptions for determination, the low, medium and high estimates of the impa
ct of HIV/AIDS in India. Some of the costs were not included in the present
analysis: (i) use of antiviral AZT, (ii) cost of retraining of new workfor
ce, (iii) cost of strengthening of health care system, (iv) cost of researc
h and development, (v) cost of communication activities, (vi) cost of preve
ntion of vertical transmission, and (vii) the intangible cost of pain and s
uffering to the patients and their families. Results: The total cumulative
number of HIV-infected persons in India until 1995 was estimated to be 1.5
million (low estimate), 2.5 million (medium estimate) and 4.5 million (high
estimate). The estimated total annual cost (in billion Rupees) of HIV/AIDS
in India under low, medium and high assumptions was 6.73, 20.16 and 59.19,
respectively. Cost of treatment of AIDS and loss in productivity were the
two major components of the cost. Conclusions: The estimated annual cost of
HIV/AIDS appears to be about 1% of the GDP of India if based on high assum
ptions. However, as mentioned earlier, all costs of HIV have not been taken
into account. Its significance has to be assessed in the context of annual
growth of GDP (3.5%) and cost of other major diseases in India. (C) 1999 E
lsevier Science Ireland Ltd. All rights reserved.