Cyano diallylamine additions to glycoside and nucleoside aldehydes and itsapplication to the synthesis of polyoxin L and uracil polyoxin C

Three efficient, high yielding syntheses of precursors (1) of carbamoylpoly oxamic acid from L-arabinose, based on the simultaneous addition of the aci d and amine functionalities, are described. Utilizing the same methodology and uridine as the starting material, an expedient 3 step (61% overall yiel d) synthesis of protected uracil polyoxin C (or the nucleoside moiety of po lyoxin L, 2), is also described.