Kw. Hinchcliff et al., EFFECT OF RACING ON SERUM SODIUM AND POTASSIUM CONCENTRATIONS AND ACID-BASE STATUS OF ALASKAN SLED DOGS, Journal of the American Veterinary Medical Association, 210(11), 1997, pp. 1615
Objective--To examine the effect of participation in a long-distance r
ace on serum electrolyte concentrations, estimated exchangeable cation
content, and acid-base status of Alaskan sled dogs. Design--Prospecti
ve study. Animals--9 male and 5 female, sexually intact, physically fi
t Alaskan sled dogs between 18 and 48 months old. Procedure--Body weig
ht was recorded, and blood samples were collected from dogs before, du
ring, and after a 300-mile race. Results--Serum sodium and potassium c
oncentrations decreased during the race, as did serum total protein, a
lbumin, and globulin concentrations and PCV. Effects on acid-base stat
us were minimal. Body weight and estimated total exchangeable cation c
ontent in dogs also decreased significantly during the race. Clinical
Implications--Prolonged running is associated with decreases in serum
cation concentration and estimated total exchangeable cation content i
n dogs, as in human beings and horses. However, the mechanism of the d
ecrease in serum cation concentration likely differs among species. Cl
inical abnormalities associated with cation depletion were not observe
d in the dogs in this study.