Two young dogs became acutely ill following ingestion of fallen fruit
from a chinaberry tree (Melia azedarach). Clinical signs of poisoning
developed within hours and were characteristic of gastrointestinal and
CNS disturbances. Despite prompt and aggressive emergency treatment,
neither dog survived longer than 36 hours after the onset of clinical
signs of poisoning. Necropsy of 1 dog revealed severe renal congestion
, moderate hepatic congestion, and a moderate amount of serosanguineou
s fluid in the abdominal cavity. To the best of our knowledge, previou
s reports of chinaberry poisoning of dogs are lacking. However, chinab
erry poisoning is well documented in human beings and other animals. T
herefore, we strongly recommend that dogs, in addition to other animal
s, have restricted access to chinaberry trees and their fruit to preve
nt potential poisoning.