On the use of Trametes versicolor laccase for the conversion of 4-methyl-3-hydroxyanthranilic acid to actinocin chromophore

Authors
Osiadacz, J Al-Adhami, AJH Bajraszewska, D Fischer, P Peczynska-Czoch, W
Citation
J. Osiadacz et al., On the use of Trametes versicolor laccase for the conversion of 4-methyl-3-hydroxyanthranilic acid to actinocin chromophore, J BIOTECH, 72(1-2), 1999, pp. 141-149
Citations number
20
Categorie Soggetti
Biotecnology & Applied Microbiology",Microbiology
Journal title
JOURNAL OF BIOTECHNOLOGY
ISSN journal
01681656 → ACNP
Volume
72
Issue
1-2
Year of publication
1999
Pages
141 - 149
Database
ISI
SICI code
0168-1656(19990611)72:1-2<141:OTUOTV>2.0.ZU;2-P
Abstract
Laccase isolated from Trametes versicolor was immobilized in polyacrylamide gel and used for the conversion of 4-methyl-3-hydroxyanthranilic acid to 2 -amino-4,6-dimethyl-3-phenoxazinone-1,9-carboxylic acid (actinocin) which i s a phenoxazinone chromophore occuring in actinomycins. The reaction procee ded successfully in aqueous media and in 60% acetonitrile. (C) 1999 Elsevie r Science B.V. All rights reserved.