J. Osiadacz et al., On the use of Trametes versicolor laccase for the conversion of 4-methyl-3-hydroxyanthranilic acid to actinocin chromophore, J BIOTECH, 72(1-2), 1999, pp. 141-149
Laccase isolated from Trametes versicolor was immobilized in polyacrylamide
gel and used for the conversion of 4-methyl-3-hydroxyanthranilic acid to 2
-amino-4,6-dimethyl-3-phenoxazinone-1,9-carboxylic acid (actinocin) which i
s a phenoxazinone chromophore occuring in actinomycins. The reaction procee
ded successfully in aqueous media and in 60% acetonitrile. (C) 1999 Elsevie
r Science B.V. All rights reserved.