Objective: To determine the psychiatric risk factors for suicide in adolesc
ents with disruptive disorders. Method: Fifty-nine adolescent suicide compl
eters and 18 community controls, both having a probable or definite current
DSM-III diagnosis of disruptive disorders, were compared. Results: adolesc
ents with disruptive disorders who committed suicide had higher rates of cu
rrent substance abuse, past suicide attempt, family history of substance ab
use, and family history of mood disorder than disruptive community controls
. Conclusions: Disruptive adolescents appear to be at risk for completed su
icide when comorbid substance abuse and past history of suicide attempt are
present. The risk increases if the adolescents have a past history of phys
ical abuse and if they have parents with substance abuse and mood disorders
. Clinicians should be aware of these risk factors and implement active int
erventions to prevent suicide. Treatment should focus on treating not only
the adolescents, but also their family members. The findings of this study
also highlight the need for future research in the prevention of suicide in
adolescents with disruptive disorders and comorbid substance abuse.