M. Kakimoto et al., Effects of Fujibitol, a remedy for nasal symptoms of immediate and delayedtype allergic reactions, METH FIND E, 21(5), 1999, pp. 353-356
Citations number
11
Categorie Soggetti
Pharmacology & Toxicology
Journal title
METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY
The effects of Fujibitol, a remedy for the nasal symptoms of immediate and
delayed type allergic reactions were studied. Fujibitol inhibited active sy
stemic anaphylaxis in mice, heterologous passive cutaneous anaphylaxis (PCA
) in rats, Masugi's nephritis in rats and delayed type hypersensitivity ind
uced by picryl chloride in mice, but did not affect homologous PCA or immun
e complex-induced glomerulonephritis in rats. These results suggested that
Fujibitol is effective for treatment of allergy-induced inflammation since
Ige and type IV allergic reactions were inhibited. (C)1999 Prous Science. A
ll rights reserved.