Effects of Fujibitol, a remedy for nasal symptoms of immediate and delayedtype allergic reactions

Authors
Kakimoto, M Takasugi, N Fuwa, T Saito, H Sugimoto, Y Kamei, C
Citation
M. Kakimoto et al., Effects of Fujibitol, a remedy for nasal symptoms of immediate and delayedtype allergic reactions, METH FIND E, 21(5), 1999, pp. 353-356
Citations number
11
Categorie Soggetti
Pharmacology & Toxicology
Journal title
METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY
ISSN journal
03790355 → ACNP
Volume
21
Issue
5
Year of publication
1999
Pages
353 - 356
Database
ISI
SICI code
0379-0355(199906)21:5<353:EOFARF>2.0.ZU;2-E
Abstract
The effects of Fujibitol, a remedy for the nasal symptoms of immediate and delayed type allergic reactions were studied. Fujibitol inhibited active sy stemic anaphylaxis in mice, heterologous passive cutaneous anaphylaxis (PCA ) in rats, Masugi's nephritis in rats and delayed type hypersensitivity ind uced by picryl chloride in mice, but did not affect homologous PCA or immun e complex-induced glomerulonephritis in rats. These results suggested that Fujibitol is effective for treatment of allergy-induced inflammation since Ige and type IV allergic reactions were inhibited. (C)1999 Prous Science. A ll rights reserved.