Glaucoma is the third-most-frequent cause of blindness in the world, with a
total of 5.2 million blind people as a result of this disease; 80 % live i
n developing countries. In Paraguay, after cataract it is the second-most-f
requent-cause. Early detection of the risk factors and groups can help to a
void progress of this disease. Trauma, cataract and infectious uveitis repr
esent special risks for developing secondary glaucoma, which is a more freq
uent cause of blindness in third-world countries than in industrialized nat
ions. Until now there has been little data regarding the causes, disease co
urse, and options for therapy. Therefore, secondary glaucoma was examined i
n Paraguay to obtain information on the situation in Latin America. The aim
of the study was to explore the causes of secondary glaucoma for programs
concerning prevention and therapy. From November 1996 to February 1997 pati
ents with secondary glaucoma were examined at the University Hospital of As
uncion, Paraguay. After the clinical examination the secondary glaucomas we
re classified. Patients with primary glaucoma were included in the same per
iod of time as well in order to get the rate of secondary glaucoma. Altoget
her 293 patients were examined: 61 with secondary and 232 with primary glau
coma. The causes of secondary glaucoma in 73 eyes were: 20 (27 %) with pseu
doexfoliation glaucoma, 19 (26 %) with post-traumatic glaucoma, 16 (22 %) w
ith neovascular glaucoma, 4 (5 %) with lens-related glaucoma, 3 (4 %) with
glaucoma associated with ocular surgery, 2 (3 %) with pigmentary and 2 (3 %
) with corticoid-induced glaucoma. A ratio of 4:1 primary glaucomas to seco
ndary glaucomas was found. The development of special measures for preventi
on and early therapy is only possible if the causes of this severe disease
are explored. The results of this study represent basic information and cou
ld help to introduce of prevention programs.