Secondary amoebic eye infections in mice due to Acanthamoeba sp.

The aim of the present study was to determine the occurrence of eye infecti ons accompanying the infection of the central nervous system and to demonst rate the possible tissue affinity of different strains of amoebae in subseq uent infections. The results obtained demonstrate a clear correlation betwe en the occurrence of eye infection and the degree of virulence of the strai ns. Amoebae isolated from eyeballs and other organs of dead mice did not ex hibit any specificity in relation to the organs in subsequent infections. I rrespective of the place of isolation - be it eye or brain - in the subsequ ent passages, the amoebae were most often found in the brain and lungs, fol lowed only then by the eye of the infected animals.