Azaanthraquinone: An antimicrobial alkaloid from Mitracarpus scaber

Authors
Okunade, AL Clark, AM Hufford, CD Oguntimein, BO
Citation
Al. Okunade et al., Azaanthraquinone: An antimicrobial alkaloid from Mitracarpus scaber, PLANTA MED, 65(5), 1999, pp. 447-448
Citations number
11
Categorie Soggetti
Pharmacology & Toxicology
Journal title
PLANTA MEDICA
ISSN journal
00320943 → ACNP
Volume
65
Issue
5
Year of publication
1999
Pages
447 - 448
Database
ISI
SICI code
0032-0943(199906)65:5<447:AAAAFM>2.0.ZU;2-Y
Abstract
An ethanolic extract of the aerial parts of Mitracarpus scaber demonstrated good antimicrobial activity. Bioassay directed fractionation of this extra ct led to the isolation of benz[g]isoquinoline-5,10-dione (1) as an active component. Compound 1 showed significant in vitro inhibitory activity again st the AIDS-related pathogens.