Biological activity of the essential oil of Myrcianthes sp nov "black fruit" from Monteverde, Costa Rica

Authors
Setzer, WN Setzer, MC Moriarity, DM Bates, RB Haber, WA
Citation
Wn. Setzer et al., Biological activity of the essential oil of Myrcianthes sp nov "black fruit" from Monteverde, Costa Rica, PLANTA MED, 65(5), 1999, pp. 468-469
Citations number
19
Categorie Soggetti
Pharmacology & Toxicology
Journal title
PLANTA MEDICA
ISSN journal
00320943 → ACNP
Volume
65
Issue
5
Year of publication
1999
Pages
468 - 469
Database
ISI
SICI code
0032-0943(199906)65:5<468:BAOTEO>2.0.ZU;2-O
Abstract
The leaf essential oil of an undescribed species of Myrcianthes has been ob tained from Monteverde, Costa Rica. The essential oil exhibits in vitro cyt otoxic activity against Hep-G2 and SK-Mel-28 human tumor cell lines. A GC/M S analysis shows the essential oil to be composed of 2-heptanol, alpha-pine ne, beta-pinene, limonene, cineole, and alpha-terpineol. alpha-Pinene, beta -pinene, and limonene account for the cytotoxic activity of the leaf essent ial oil of Myrcianthes sp. nov. "black fruit".