Synthesis of two hyaluronic-acid-related oligosaccharide 4-methoxyphenyl glycosides having a beta-D-glucuronic acid residue at the reducing end

Authors
Halkes, KM Slaghek, TM Hypponen, TK Kamerling, JP Vliegenthart, JFG
Citation
Km. Halkes et al., Synthesis of two hyaluronic-acid-related oligosaccharide 4-methoxyphenyl glycosides having a beta-D-glucuronic acid residue at the reducing end, POL J CHEM, 73(7), 1999, pp. 1123-1131
Citations number
20
Categorie Soggetti
Chemistry
Journal title
POLISH JOURNAL OF CHEMISTRY
ISSN journal
01375083 → ACNP
Volume
73
Issue
7
Year of publication
1999
Pages
1123 - 1131
Database
ISI
SICI code
0137-5083(199907)73:7<1123:SOTHO4>2.0.ZU;2-#
Abstract
Synthesis of two hyaluronic-acid-related oligosaccharides, the 4-methoxyphe nyl beta-glycosides of beta-D-GlcpA-(1 --> 3)-beta-D-GlcpNAc-(1 --> 4)-D-Gl cpA and beta-D-GlcpA(1 --> 3)-beta-D-clcpNAc-(1 --> 4)-beta-D-GlcpA-(1 --> 3)-beta-D-GlcpNAc-(1 --> 4)-D-GlcpA, is described. D-Glucopyranosyluronic a cid residues were obtained by selective oxidation at C6 of corresponding D- glucopyranosyl residues after construction of the oligosaccharide backbones , using pyridinium dichromate and acetic anhydride.