Multistep mechanism for "hydride" transfer in the redox reactions induced by NAD(P)H- and NAD(P)(+)-models

Authors
Yasui, S Okamura, M Fujii, M
Citation
S. Yasui et al., Multistep mechanism for "hydride" transfer in the redox reactions induced by NAD(P)H- and NAD(P)(+)-models, REV HET CHE, 20, 1999, pp. 145-165
Citations number
55
Categorie Soggetti
Chemistry
Journal title
REVIEWS ON HETEROATOM CHEMISTRY
ISSN journal
09156151 → ACNP
Volume
20
Year of publication
1999
Pages
145 - 165
Database
ISI
SICI code
0915-6151(1999)20:<145:MMF"TI>2.0.ZU;2-#
Abstract
The mechanistic studies presented to date concerning reductions by NAD(P)H models as well as oxidations by NAD(P)(+) models are outlined. Particularly emphasized are studies about how a net "hydride" is transferred from an NA D(P)H model to a substrate. A multistep mechanism including the initial ele ctron transfer is shown to be more likely than a single-step mechanism.