Retinoid therapy: Compatible skin care

Authors
Citation
Y. Appa, Retinoid therapy: Compatible skin care, SKIN PH APP, 12(3), 1999, pp. 111-119
Citations number
5
Categorie Soggetti
da verificare
Journal title
SKIN PHARMACOLOGY AND APPLIED SKIN PHYSIOLOGY
ISSN journal
14222868 → ACNP
Volume
12
Issue
3
Year of publication
1999
Pages
111 - 119
Database
ISI
SICI code
1422-2868(199905/06)12:3<111:RTCSC>2.0.ZU;2-G
Abstract
Topically applied tretinoin (a retinoid) has been used for over 25 years to treat acne and disorders of keratinization. Now, tretinoin emollient cream , 0.05% (Renova(R)), may be prescribed for the treatment of photodamaged an d chronologically aged skin, in conjunction with appropriate skin care and sun protection routines. Mild to moderate cutaneous side effects to topical tretinoin, such as xerosis, peeling, erythema and subjective irritation, a re experienced by a majority of patients undergoing retinoid therapy. Resul ts of clinical compatibility testing show that concomitant use of effective moisturizers, mild cleansers and daily sunscreens greatly enhance skin tol erance and patient comfort. A frequently prescribed regimen for topical tre atment of photodamaged skin includes a combination of tretinoin and glycoli c acid. While many clinicians report the use of both these agents for the m anagement of their patients, little information exists in the literature ab out their compatibility in concomitant use. The results of a double-blind c linical study demonstrate that daytime usage of one of two 8% glycolic acid lotions in addition to nightly applications of Renova was well tolerated a s part of a comprehensive skin care and sun protection program.