Interionic and intermolecular interactions in ion-exchange and sorption systems involving physiologically active substances

This paper reviews the results obtained by studying the sorption of physiol ogically active substances (PAS) of different types such as, amino acids, n ucleotides and melanoidins on ion exchangers and non-ionogenic sorbents. Th e review is mainly focused upon the mechanisms of interaction of PAS molecu les in the sorbent phase. The contribution of ion-ionic, ion-molecular and intermolecular interactions to the overall sorption effect is discussed. Th e results of studying ion-exchange isothermal supersaturation of amino acid solutions on anion exchangers are reported and discussed. The mechanisms o f aging of ion-exchange materials in the course of recovery of PAS from fer mentation broths and hydrolysates are proposed.