Synthesis and lipase-catalyzed enantiotope selective acetylation of 2-benzoyloxy-1,3-propanediol

Authors
Bodai, V Novak, L Poppe, L
Citation
V. Bodai et al., Synthesis and lipase-catalyzed enantiotope selective acetylation of 2-benzoyloxy-1,3-propanediol, SYNLETT, (6), 1999, pp. 759-761
Citations number
17
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNLETT
ISSN journal
09365214 → ACNP
Issue
6
Year of publication
1999
Pages
759 - 761
Database
ISI
SICI code
0936-5214(199906):6<759:SALESA>2.0.ZU;2-S
Abstract
Preparation and porcine pancreatic lipase (PPL)-catalyzed enantiotope selec tive acetylation of the prochiral 2-benzoyloxy-1,3-propanediol (la) is desc ribed. The reaction with PPL and vinyl acetate gave monoacetate (2a) of 96 % e.e.