Two synthetic routes are proposed to prepare phosphoenolpyruvate derivative
s of xylose as models of potent phosphoenol pyruvate lyase inhibitors : a P
erkow reaction between beta-bromo-alpha-ketoester derivatives of xylose 4 a
nd trimethylphosphite, and a new reaction between alpha-bromoglycidic ester
derivatives of xylose 3 and trimethylphosphite.