We compared the RE1B and T. King (TK) serotype 1 isolates of Marek's diseas
e virus (MDV) in vivo. Body and organ weights, mortality, and lesions indic
ated that the TK inoculum established early infection more efficiently than
RB1B and did greater damage to the bursa of Fabricius and thymus. Subseque
nt studies showed that the TK inoculum that we used contained chicken infec
tious anemia virus (CIAV). Therefore, pathogenicity profiles shown here sho
uld be interpreted with the presence of CIAV contamination in the TK stock
in mind.