Acoustic tumor growth: Implications for treatment choices

Background: Knowledge of acoustic neuroma (AN) growth is essential for trea tment planning. Methods: A retrospective analysis of 119 patients with AN (mean age, 65 yea rs; range, 37-84 years) followed with interval magnetic resonance imagings (MRIs) was performed. Change in maximum tumor dimension as a function of fo llow-up period was analyzed. Results: Overall, maximum tumor dimension increased >2 mm in only 30% of pa tients. Of those that grew, the mean growth rate was 3.8 mm/year (maximum, 25 mm/year). Age, gender, and laterality did not predict growth. Most tumor s that grew (86.1%) were <20 mm at presentation. However, tumors >20 mm wer e statistically more likely to grow (71%, p = 0.028). Conclusions: Most ANs followed with periodic MRIs do not grow. Available cl inical information usually cannot predict growth. Serial MRIs are advocated for all patients treated with observation.