Alcohol and drug use have been shown to contribute to the onset of traumati
c spinal cord injury and to be a marker for later onset substance abuse iss
ues. Admission toxicology (drug and alcohol) screens were collected from 87
consecutive rehabilitation medicine patients with a diagnosis of acute tra
umatic spinal cord injury. Forty-six patients (53%) presented with positive
screens (44% alcohol only, 30% drug only, 26% both). Seventy-five percent
of those with positive alcohol screens met state criteria for alcohol intox
ication (blood alcohol level, greater than or equal to 0.08 mg/dl). Compare
d with individuals with negative screens, those with positive screens were
significantly (P < 0.05) younger and unmarried. Compared with nonviolence-r
elated spinal cord injury, patients with violence-related spinal cores inju
ry (gunshot wound and assault) were significantly (P < 0.01) more likely to
have positive admission toxicology screens (76% v 41%), drug screens (62%
v 14%), and intoxication screens (72% v 34%). Rehabilitation outcome compar
isons between those with positive and negative screens revealed similar len
gth of stay, admission and discharge Functional independence Measure (FIM(T
M)) scores, FIM change scores, and FIM efficiency scores. This study has im
portant implications with regard to substance abuse issues and their impact
on traumatic spinal cord injury outcome, which may assist in better target
ing prevention.