Background: It is not known whether physical activity is effective in reduc
ing the risk for hypertension.
Objective: To investigate the association of the duration of the walk to wo
rk and leisure-time physical activity with the risk for hypertension.
Design: Prospective cohort study.
Setting: Work site in Osaka, Japan.
Participants: 6017 Japanese men 35 to 60 years of age with systolic blood p
ressure less than 140 mm Hg, diastolic blood pressure less than 90 mm Hg, n
ormal glucose intolerance, and no history of hypertension or diabetes at ba
seline.
Measurements: Data on physical activity were obtained by using questionnair
es. Blood pressure was measured by using a standard technique; a value of a
t least 160/95 mm Hg was used to diagnose hypertension.
Results: During 59 784 person-years of follow-up, 626 cases of hypertension
were confirmed. The duration of the walk to work was associated with a red
uction in the risk for incident hypertension; multivariate-adjusted relativ
e risks were 1.00 for a walk of 10 minutes or less (reference category), 0.
88 (95% CI, 0.75 to 1.04) for an 11- to 20-minute walk, and 0.71 (CI, 0.52
to 0.97) for a walk of 21 minutes or more (P for trend = 0.02). For every 2
6.3 men who walk more than 20 minutes to work, one case of hypertension wil
l be prevented.
Conclusions: Walking to work and other types of physical activity decreased
the risk for hypertension in Japanese men. Regular exercise can prevent hy
pertension.