Meta-analysis is a relatively new development in medicine. It is conceptual
ly appealing, summarizing the medical literature in a rigorous manner and p
roviding clinicians with a global picture regarding the merits of intervent
ions. This process can help clinicians choose appropriate, evidence-based m
anagement options for their patients. The early enthusiasm for this approac
h has more recently been called into question. The reliability, and therefo
re the usefulness, of meta-analysis will improve as more evidence concernin
g the rigorous ways to conduct and report such studies is developed.