Although the loss of green color in senescent leaves and ripening fruits is
a spectacular natural phenomenon, research on chlorophyll breakdown has bee
n largely neglected until recently. This review summarizes knowledge about
the fate of chlorophyll in degreening tissues that has been gained during t
he past few years. Structures of end- and intermediary products of degradat
ion as well as the biochemistry of the porphyrin-cleaving reaction have bee
n elucidated. The intracellular localization of the catabolic pathway is pa
rticularly important in the regulation of chlorophyll breakdown. None of th
e genes encoding the related catabolic enzymes has so far been isolated, wh
ich makes chlorophyll degradation an area of opportunity for future researc
h.