Case of the month: Acute necrotizing myopathy (rhabdomyolysis) secondary to lovastatin and niacin.

Authors
Hill, MD Bilbao, JM
Citation
Md. Hill et Jm. Bilbao, Case of the month: Acute necrotizing myopathy (rhabdomyolysis) secondary to lovastatin and niacin., BRAIN PATH, 9(3), 1999, pp. 607-608
Citations number
8
Categorie Soggetti
Neurosciences & Behavoir
Journal title
BRAIN PATHOLOGY
ISSN journal
10156305 → ACNP
Volume
9
Issue
3
Year of publication
1999
Pages
607 - 608
Database
ISI
SICI code
1015-6305(199907)9:3<607:COTMAN>2.0.ZU;2-L
Abstract
A 54 year old man developed rhabdomyolysis one year after beginning treatme nt with a combination of lorastatin (an HMGCoA reductase inhibitor) and nia cin. Muscle biopsy showed a severe necrotizing myopathy affecting both fibr e types. Recovery occured gradually with cessation of medication. The spect rum of cholesterol lowering agent myopathy may include delayed cases of unu sual severity.