Microwave endometrial ablation: development, clinical trials and outcomes at three years

Citation
Da. Hodgson et al., Microwave endometrial ablation: development, clinical trials and outcomes at three years, BR J OBST G, 106(7), 1999, pp. 684-694
Citations number
56
Categorie Soggetti
Reproductive Medicine","da verificare
Journal title
BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY
ISSN journal
14700328 → ACNP
Volume
106
Issue
7
Year of publication
1999
Pages
684 - 694
Database
ISI
SICI code
1470-0328(199907)106:7<684:MEADCT>2.0.ZU;2-#
Abstract
Objective To describe the introduction of microwave endometrial ablation to clinical practice, and to report the outcomes three years after endometria l ablation. Design A clinical trial using prototype microwave endometrial ablation equi pment. Setting District general hospital. Population Forty-three women with completed families and with failed medica l management for menorrhagia were treated with microwave endometrial ablati on between October 1994 and April 1995. Main outcome measures A statement of perceived menstrual loss and satisfact ion supported by a menstrual symptom questionnaire score. Dysmenorrhoea was graded as a measure of described severity. Treatment time. Results Forty-three women had a total of 46 treatments. Mean treatment time : n = 43, was 141 seconds (50-310). Amenorrhoea: n = 16; 37.2%. Very light periods/discharge: It = 11; 25.6%. Improved periods and woman satisfied: n = 9; 20.9%. Improved periods and woman not satisfied: n =1; 2.3%. Overall s atisfaction at three years is 83.7%, Moderate (55.8%) or severe (27.9%) dys menorrhoea preoperatively had improved to 11.6% and 6.8% respectively at th ree years. Three re-treatments and four hysterectomies will be discussed. Conclusions Microwave endometrial ablation is a new treatment for dysfuncti onal uterine bleeding using the application of microwave energy to the endo metrium. This results in a rapid but restricted depth of intrauterine heati ng avoiding hysteroscopic fluid, operative haemorrhage and earthing risks. The technique is simple to learn and perform. Women report a high level of satisfaction three years after microwave endometrial ablation.