Vitamin K-1 purification process in a molecular evaporator

A purification process of crude phytomenadione (vitamin K-1) by molecular d istillation using a short-path wiped-film evaporator and by adsorption is s tudied. The purification procedure is documented by evaluation of samples f rom the individual stages of the process by means of UV and visible spectro scopies, TLC, refraction index measurements, and further methods. Satisfact ory parameters were found in a material obtained as the distillate from the molecular evaporator, particularly after its adsorption on a phenolformald ehyde-resin-based ion exchanger.