Long-term persistence of immunoglobulin A (IgA) and IgM antibodies againsthuman cytomegalovirus in solid-organ transplant recipients

Authors
Eing, BR Baumeister, HG Kuehn, JE May, G
Citation
Br. Eing et al., Long-term persistence of immunoglobulin A (IgA) and IgM antibodies againsthuman cytomegalovirus in solid-organ transplant recipients, CL DIAG LAB, 6(4), 1999, pp. 621-623
Citations number
17
Categorie Soggetti
Immunology
Journal title
CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY
ISSN journal
1071412X → ACNP
Volume
6
Issue
4
Year of publication
1999
Pages
621 - 623
Database
ISI
SICI code
1071-412X(199907)6:4<621:LPOIA(>2.0.ZU;2-8
Abstract
The retrospective analysis of 494 solid-organ transplant recipients reveale d that during the follow-up period (mean duration, 3.2 years) 184 (88%) of 209 anti-human cytomegalovirus (HCMV) immunoglobulin A (IgA)positive patien ts remained IgA positive, as did 128 (74.85%) of 171 anti-HCMV IgM-positive patients. We conclude that anti-HCMV IgA and IgM testing for management of clinically relevant HCMV infections in solid-organ transplant recipients i s dispensable.