Two cases of elastofibroma dorsi (one bilateral, one unilateral) in the per
iscapular and infrascapular region of two male patients are described. Magn
etic resonance imaging revealed a tumorous mass of typical low signal inten
sity with interspersed areas of high signal intensity on T1 and T2 weighted
spin echo sequences. In contrast to previous studies that reported mild en
hancement within elastofibromas after administration of intravenous contras
t agent, marked enhancement in one of two elastofibromas was found. This is
considered to be atypical for benign lesions. After biopsy and histopathol
ogic examination, an intended marginal resection was performed in both case
s. Laboratory values, radiographs, and computed tomography may not be helpf
ul in differentiating elastofibroma from malignant tumors. In addition to c
areful clinical investigation, magnetic resonance imaging is the method of
choice leading to a presumptive diagnosis. Because marked enhancement on co
ntrast agent images was observed, which is characteristic for malignant tum
ors, one should be aware that this feature does not exclude the presence of
elastofibroma. Accurate diagnosis should be made preferably by biopsy and
histopathologic evaluation before additional treatment is administered. Mar
ginal resection is curative in patients with symptoms. Despite its low inci
dence, this pseudotumoral lesion should be known generally to differentiate
it from malignant tumors and to avoid unnecessary wide or radical surgery.