B. Rogina et Sl. Helfand, SPATIAL AND TEMPORAL PATTERN OF EXPRESSION OF THE WINGLESS AND ENGRAILED GENES IN THE ADULT ANTENNA IS REGULATED BY AGE-DEPENDENT MECHANISMS, Mechanisms of development, 63(1), 1997, pp. 89-97
The spatial and temporal pattern of expression of enhancer trap lines
reporting on the wingless (wg) and engrailed (en) genes was characteri
zed in the adult antenna of Drosophila melanogaster. The time courses
of expression seen for wg and en, although different from each other,
reveal a complex well-controlled pattern of temporal expression, provi
ding evidence that regulatory mechanisms are preserved throughout the
life span of the adult fly. Altering the life span demonstrates that t
he temporal patterns of expression of both wg and en are linked to lif
e span. These studies suggest that the expression of wg and en in the
adult antenna is controlled by age-dependent mechanisms. (C) 1997 Else
vier Science Ireland Ltd.