Environmental exposure to volatile organic compounds among workers in Mexico city as assessed by personal monitors and blood concentrations

Benzene, an important component in gasoline, is a widely distributed enviro nmental contaminant that has been linked to known health effects in animals and humans, including leukemia. In Mexico City, environmental benzene leve ls, which may be elevated because of the heavy traffic and the poor emissio n control devices of older vehicles, may pose a health risk to the populati on. To assess the potential risk, portable passive monitors and blood conce ntrations were used to survey three different occupational groups in Mexico City. Passive monitors measured the personal exposure of 45 workers to ben zene, ethylbenzene, toluene, o-xylene and m-/p-xylene during a work shift. Blood concentrations of the above volatile organic compounds (VOCs), methyl tert-butyl ether, and styrene were measured at the beginning and the end o f a work shift. Passive monitors showed significantly higher (p > 0.0001) b enzene exposure levels among service station attendants (median = 330 mu g/ m(3); range 130-770) as compared to street vendors (median = 62 mu g/m(3); range 49-180) and office workers (median = 44 mu g/m(3), range 32-67). Base line blood benzene levels (BBLs) for these groups were higher than those re ported for similar populations from Western countries (median = 0.63 mu g/L , n = 24 for service station attendants; median = 0.30 mu g/L, n = 6 for st reet vendors; and median = 0.17 mu g/L, n = 7 for office workers). Nonsmoki ng office workers who were nonoccupationally exposed to VOCs had BBLs that were more than five times higher than those observed in a nonsmoking U.S. p opulation. BBLs of participants did not increase during the work shift, sug gesting that because the participants were chronically exposed to benzene, complex pharmacokinetic mechanisms were involved. Our results highlight the need for more complete studies to assess the potential benefits of setting environmental standards for benzene and other VOCs in Mexico.