(R)-(+) and (S)-(-) ethyl 4,4,4-trifluoro-3-hydroxy butanoate by enantioselective Baker's yeast reduction

Authors
Davoli, P Forni, A Moretti, I Prati, F Torre, G
Citation
P. Davoli et al., (R)-(+) and (S)-(-) ethyl 4,4,4-trifluoro-3-hydroxy butanoate by enantioselective Baker's yeast reduction, ENZYME MICR, 25(1-2), 1999, pp. 149-152
Citations number
19
Categorie Soggetti
Biotecnology & Applied Microbiology",Microbiology
Journal title
ENZYME AND MICROBIAL TECHNOLOGY
ISSN journal
01410229 → ACNP
Volume
25
Issue
1-2
Year of publication
1999
Pages
149 - 152
Database
ISI
SICI code
0141-0229(19990715)25:1-2<149:(A(E4B>2.0.ZU;2-J
Abstract
(R)-(+) and (S)-(-) ethyl 4,4,4-trifluoro-3-hydroxybutanoate are obtained b oth by enantioselective Baker's yeast reduction of ethyl 4,4,4-trifluoro-3- oxobutanoate in the presence of allyl bromide or allyl alcohol. The two add itives act as inhibitors of Si or Re yeast-enzymes, respectively. (C) 1999 Elsevier Science Inc. All rights reserved.