EFFECT OF STIMULATING CYCLIC GUANOSINE-MONOPHOSPHATE (CGMP) PATHWAY ON BOVINE SPERM PARAMETERS

Authors
HASSAN MS ISMAIL TIM MANSOUR MM SHERIEF M ABDOU MSS
Citation
Ms. Hassan et al., EFFECT OF STIMULATING CYCLIC GUANOSINE-MONOPHOSPHATE (CGMP) PATHWAY ON BOVINE SPERM PARAMETERS, Reproduction in domestic animals, 32(3), 1997, pp. 167-169
Citations number
22
Categorie Soggetti
Reproductive Biology","Veterinary Sciences
Journal title
Reproduction in domestic animals → ACNP
ISSN journal
09366768
Volume
32
Issue
3
Year of publication
1997
Pages
167 - 169
Database
ISI
SICI code
0936-6768(1997)32:3<167:EOSCG(>2.0.ZU;2-1
Abstract
The present study aimed to investigate the influence on bovine spermat ozoa of nitroglycerin (1,2,3-propanetriol trinitrate), which is known for its stimulating effect on the cGMP pathway. Results revealed that the motility of spermatozoa from the nitroglycerin-treated samples was significantly improved compared with the control samples and this imp rovement was demonstrable for up to 2 hours. Meanwhile, live sperm per centage and the percentage of spermatozoa with intact acrosomes were n ot affected. In addition, significant improvement in the cervical mucu s penetrability of spermatozoa from the treated samples could be detec ted. It could, therefore, be inferred that cGMP plays an important rol e in enhancing bovine sperm motility.