CD5 expression in human B-cell populations

Authors
Youinou, P Jamin, C Lydyard, PM
Citation
P. Youinou et al., CD5 expression in human B-cell populations, IMMUNOL TOD, 20(7), 1999, pp. 312-316
Citations number
57
Categorie Soggetti
Immunology
Journal title
IMMUNOLOGY TODAY
ISSN journal
01675699 → ACNP
Volume
20
Issue
7
Year of publication
1999
Pages
312 - 316
Database
ISI
SICI code
0167-5699(199907)20:7<312:CEIHBP>2.0.ZU;2-X
Abstract
The origin of CD5(+) B cells remains controversial. The differential respon se to ligation of CD5 resulting in apoptosis or proliferation provides insi ght into its roles in distinct human B cells. Here,Pierre Youinou, Christop he Jamin and Peter Lydyard review current knowledge of B-1 and B-2 cells, a nd proposer that CD5 has different functions when expressed by different B- cell subpopulations.