T-cell function in newborn mice and humans

Authors
Adkins, B
Citation
B. Adkins, T-cell function in newborn mice and humans, IMMUNOL TOD, 20(7), 1999, pp. 330-335
Citations number
60
Categorie Soggetti
Immunology
Journal title
IMMUNOLOGY TODAY
ISSN journal
01675699 → ACNP
Volume
20
Issue
7
Year of publication
1999
Pages
330 - 335
Database
ISI
SICI code
0167-5699(199907)20:7<330:TFINMA>2.0.ZU;2-P
Abstract
Neonates mount poor immune responses, and if has been assumed that neonatal T cells differ qualitatively from adult T cells. Here, Becky Adkins discus ses this issue ill the light of recent data indicating that T cells in neon ates ave developmentally mature in their capacity to mount protective Th1-t ype and cytotoxic T lymphocyte responses.