Im. El-deen et Me. Abd El-fattah, Synthesis and biological activity of some heterocyclic compounds containing quinoxaline and coumarin moieties, I J HET CHE, 8(4), 1999, pp. 319-324
2,3-Dichloroquinoxaline (2) has been condensed with 7,8-dihydroxy-4-methylc
oumarin to give the 1,4-dioxine (4). 2,3-Dichloroquinoxaline (2) on reactio
ns with 4-hydroxycoumarin, 7-hydroxy-4-methylcoumarin and acid hydrazide ga
ve either the 2,3-(dicoumarin-4-yloxy)-quinoxaline (6) or the 2,3-di (-4-me
thylcoumarin-7-yloxy) quinoxaline (7) or the 2-chloro-3-(coumarin-4-yloxy)
quinoxaline (8) or the 2-chloro-3-(4-methylcoumarin-7-yloxy) quinoxaline (9
) or the ditriazoloquinoxaline (14) or the oxadiazinoquinoxaline (16) depen
ding on the relative ratios of the reactants and the reaction conditions.